Erythropoietin (pronounced /ɨˌɹɪθɹoʊˈpɔɪɨtɨn/, /ɨˌɹɪθɹoʊˈpɔɪtən/, or /ɨˌɹiːθɹoʊ-/) or EPO is a glycoprotein hormone that controls erythropoiesis, or red blood cell production. It is a cytokine for erythrocyte (red blood cell) precursors in the bone...

Mircera

x Granulocyte colony-stimulating factor

BV: Therapeutic Molecule

Filgrastim

Granulocyte colony-stimulating factor (G-CSF or GCSF) is a colony-stimulating factor hormone. It is a glycoprotein, growth factor or cytokine produced by a number of different tissues to stimulate the bone marrow to produce granulocytes and stem...

Pegfilgrastim

x Vascular endothelial growth factor

Macugen

Vascular endothelial growth factor (VEGF) a sub-family of growth factors, more specifically of platelet-derived growth factor family of cystine-knot growth factors. They are important signaling proteins involved in both vasculogenesis (the de novo...

Bevacizumab

Ranibizumab

x HER2/neu

Trastuzumab

HER2/neu (also known as ErbB-2, ERBB2) stands for "Human Epidermal growth factor Receptor 2" and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth...

x CD20

Protein

x Epidermal growth factor receptor

Cetuximab

The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the...

Panitumumab

x Estradiol

Drug

Estrasorb

Estradiol (17β-estradiol) (also oestradiol) is a sex hormone. Mislabelled the "female" hormone, it is also present in males; it represents the major estrogen in humans. Estradiol has not only a critical impact on reproductive and sexual functioning,...

Hormone

BV: Therapeutic Molecule

x CD20

Rituximab

CD20 is a non-glycosylated phosphoprotein expressed on the surface of all mature B-cells. Membrane-spanning 4-domains, subfamily A, member 1, also known as MS4A1, is a human gene. This gene encodes a member of the membrane-spanning 4A gene family....

Ibritumomab tiuxetan

Tositumomab

x F protein of RSV

Palivizumab

x Tumor necrosis factor

Adalimumab

Tumor necrosis factor (TNF, cachexin or cachectin and formally known as tumor necrosis factor-alpha) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF's primary...

Infliximab

Afelimomab

x Glycoprotein IIb/IIIa Receptor

Abciximab

x Immunoglobulin E

Omalizumab

In biology, Immunoglobulin E (IgE) is a class of antibody (or immunoglobulin "isotype") that has only been found in mammals. It plays an important role in allergy, and is especially associated with type 1 hypersensitivity. IgE has also been...

x CD52

Alemtuzumab

CD52 is a protein present on the surface of mature lymphocytes, but not on the stem cells from which these lymphocytes were derived. It is a glycosylphosphatidylinositol (GPI)--anchored antigen expressed on the all lymphocytes as well as within the...

x Interleukin 2 receptor, alpha

Protein

Basiliximab

x CD33

Gemtuzumab ozogamicin

CD33 is a transmembrane receptor expressed on cells of monocytic/myeloid lineage. It binds sialic acids, therefore is a member of the SIGLEC family of lectins. The extracellular portion of this receptor contains two immunoglobulin domains (one IgV...

Lintuzumab

x CD11a

Efalizumab

Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a human gene. ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of...

x CD3 receptor

Muromonab

In immunology, the CD3 antigen (CD stands for cluster of differentiation) is a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with a...

x glycoprotein 17-1A

Edrecolomab

x IL2 receptor

Daclizumab

The interleukin-2 receptor (IL-2R) is heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to a cytokine called interleukin 2. Three protein chains (α, β and γ) are non-covelently...

x CD40

SGN-40

CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. The protein...

x CD30

SGN-35

CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and...

x CD70

SGN-70

CD70 (Cluster of Differentiation 70) is a ligand for CD27.

SGN-75

x Tau protein

Rember

Tau proteins are microtubule-associated proteins that are abundant in neurons in the central nervous system and are less common elsewhere. They were discovered in 1975 in Marc Kirschner's laboratory at Princeton University Weingarten et al., 1975....

x CD80

Galiximab

The protein CD80 (Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7.1. Its principal mode of action is by...

x CD74

Milatuzumab

CD74 molecule, major histocompatibility complex, class II invariant chain, also known as CD74 (Cluster of Differentiation 74), is a human gene.

x CD22

Epratuzumab

CD22 or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. Generally speaking, CD22 is a regulatory molecule that prevents the overactivation of the immune system and the development of autoimmune diseases. CD22...

x CD23

Lumiliximab

CD23, also known as Fc epsilon RII, or FcεRII, is the "low affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a...

x Factor Xa

Betrixaban

x Factor X

Betrixaban

Factor X, also known by the eponym Stuart-Prower factor or as thrombokinase, is an enzyme (EC 3.4.21.6) of the coagulation cascade. It is a serine endopeptidase (protease group S1). Factor X is synthesized in the liver and requires vitamin K for its...

x ADP Receptor

PRT06O128

x P2Y12 ADP Receptor

PRT06O128

x CD2

Alefacept

CD2 (cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It has also been called T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, erythrocyte receptor and rosette receptor....

x A4 Integrin

Natalizumab

x Ctla4

Protein

Abatacept

x CEA

Arcitumomab

x Myosin

Imciromab

Myosins are a large family of motor proteins found in eukaryotic tissues. They are responsible for actin-based motility. Most myosin molecules are composed of a head, neck, and tail domain. The wide variety of myosin genes found throughout the...

x CD15

Fanolesomab

CD15 (3-fucosyl-N-acetyl-lactosamine) is a cluster of differentiation - an immunologically significant molecule. CD15 is a carbohydrate adhesion molecule (not a protein) that can be expressed on Glycoproteins, Glycolipids and Proteoglycans. It...

x Prostate Specific Membrane Antigen

Capromab

x Interleukin 13

CAT-354

Interleukin 13 (IL-13) is a cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, that is an important mediator of allergic inflammation and disease. In addition to effects on immune cells that are similar to those of the...

x Complement component 5

Eculizumab

Complement component 5 is a protein involved in the complement system. It is cleaved into C5a and C5b:

x GD2

3F8

GD2 is a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues, principally to the cerebellum and peripheral nerves in humans. The relatively...

x CA-125

Abagovomab

CA-125, also known as CA125, is an abbreviation for cancer antigen 125. CA-125 is a tumor marker or biomarker that may be elevated in the blood of some people with specific types of cancers. CA-125 is a mucinous glycoprotein and the product of the...

x EpCAM

Adecatumumab

EpCAM or 'Epithelial Cell Adhesion Molecule' is a pan-epithelial differentiation antigen that is differentially expressed on almost all carcinomas. Its constitutional function is being elucidated. It is intricately linked with the Cadherin-Catenin...

x CD62L

BioVenturist

Biomolecule table

52 Biomolecule topics

Biomolecule BioVenturist Base

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